TGON-PLUS
Each 5 ml of TGON-PLUS suspension contains:
Mefenamic Acid IP 50 mg
Paracetamol IP 125 mg
CATEGORY analgesic antipyretic and anti inflammatory agents
MODE OF ACTION
Mefenamic acid - Mefenamic acid inhibits the enzymes COX-1 and COX-2 and reduces the formation of prostaglandins and leukotrienes. It also acts as an antagonist at prostaglandin receptor sites. It has analgesic and antipyretic properties with minor anti-inflammatory activity
Paracetamol exhibits analgesic action by peripheral blockage of pain impulse generation.
It produces antipyresis by inhibiting the hypothalamic heat-regulating centre.
Its weak anti-inflammatory activity is related to inhibition of prostaglandin synthesis in the CNS.
INDICATIONS
TGON-PLUS is indicated for temporary relief of fever and discomfort due to tonsillitis,
pharyngitis, colds and "flu", and for pain and discomfort due to teething,
immunizations and tonsillectomy.
TGON-PLUS is also useful for relief of mild to moderate painful inflammatory conditions.
DOSAGE AND ADMINISTRATION
Mefenamic acid 4 to 6.5 mg/kg per dose (maximum 25 mg/kg/day)
Paracetamol 10-15 g/kg per dose upto three times daily as necessary.
Therapy with TGON-PLUS Suspension should not exceed one week
PACKING
60 ml bottle.
SALIENT FEATURES
Mefenamic acid demonstrated significantly better antipyretic activity compared to paracetamol and ibuprofen alone.
(ref: J Assoc Physicians India. 1995 Sep;43(9):614-6)
Paracetamol has faster onset of action i.e. 30 - 60 minutes
Faster onset of action of paracetamol and longer duration of action of mafenamic acid make TGON-PLUS a very good choice in controlling pain and fever in children
WARNING!
Be sure to consult your doctor before taking any medication!
"The information containes herein is not intended to cover all possible uses,directions,precautions,warnings,drug interactions, allergic reactions,or adverse effects.if you have questions about the drugs you are taking, check with your doctor"
Posted in: ANALGESIC,MEFENAMIC ACID,PAIN KILLER,PARACETAMOL,TGON - PLUS
