COMPOSITION
Each soft gelatin capsule of APPICAL A contains:
alfa calcidol 0.25 mcg
calcium carbonate 200 mg
CATEGORY nutritional - calcium supplement
MODE OF ACTION
Alfa calcidol - Alfacalcidol is a precursor of the active calcitriol. It does not require renal hydroxylation but requires 25-hydroxylation in the liver for conversion to calcitriol . t gets converted in liver to calcitriol.wihich in turn increases the calcium absorption.
Calcium - Calcium in the blood has many important roles to play: it transports nutrients across cell membranes; produces hormones and enzymes involved in digestion and metabolism; is involved in nerve cell communication; promotes blood clotting and woundhealing; and assists with muscle contractions.
INDICATIONS
Renal osteodystrophy ( defective mineralisation due to kidney disease)
Hypoparathyroidism
Secondary hyperparathyroidism
Osteoporosis
Rickets or osteomalacia
DOSAGE 1 Capsule BD or as directed by the physician.
CONTRAINDICATIONS
Hypercalcemia ,Hypersensitivity.
PRECAUTIONS
Pregnancy, lactation, renal impairment, infants, elderly
SALIENT FEATURES
Alfa calcidol is inactive synthetic metabolite of vitamin D. It increases the level of calcium slowly after getting converted to active form and therefore does not produce hypercalcemia.
alfa calcidol works independently of kidney and PTH.
WARNING!
Be sure to consult your doctor before taking any medication!
"The information containes herein is not intended to cover all possible uses,directions,precautions,warnings,drug interactions, allergic reactions,or adverse effects.if you have questions about the drugs you are taking, check with your doctor"
Posted in: APPICAL,APPICAL-A,CALCIDOL,CALCIUM SUPPLEMENT
